Paraffin, the medium used for embedding pathological tissues in pathological diagnosis

Release time:

Apr 24,2023

China is a large paraffin producer and exporter, its output has been in the world's leading position, at present China's paraffin output is about 1.7 million tons per year, paraffin exports account for about 70% of the world paraffin market share.

Paraffin, the medium used for embedding pathological tissues in pathological diagnosis

Paraffin wax is a hydrocarbon produced by the splitting of mineral oil. Its nature is very different. The melting point is in the range of 45 °C ~ 75 °C. Paraffin wax with a low melting point is milky white to the naked eye, and it is brittle to the touch. Paraffin wax with a high melting point, light yellow in meat clothing, flexible to hard to the touch, not easy to break. Paraffin wax with high melting point has high hardness, and paraffin wax with low melting point has low hardness. Generally, the melting point below 54 °C is called soft paraffin, and above 54 "C is hard paraffin.

China is a large paraffin producer and exporter, its output has been in the world's leading position, at present China's paraffin output is about 1.7 million tons per year, paraffin exports account for about 70% of the world paraffin market share. The best form of paraffin wax is emulsified wax, which has the characteristics of acid and alkali resistance, strong water solubility, stable emulsion, long shelf life, high solid content and good dispersion, and can be used in grinding, papermaking, leather, wood, agriculture, explosives, medicine, ceramics, cosmetics and automobile protection and other industries and fields. The development and research of domestic emulsified wax products can be said to be just beginning, and the varieties and specifications of wax products produced are few, so the prospects for the development of emulsified wax products are quite broad.

Sectioning paraffin is an important embedding agent applied in animal and plant tissue sectioning technology in medicine, and is the basic material for biology, medicine, pathology and immunohistochemistry. At present, there are many kinds of sliced paraffin wax used in China, high melting point paraffin wax is harder, slicing is more difficult, and the softness is not suitable, but thinner sections can be cut; Low melting point paraffin, low hardness, insufficient support for slices, it is difficult to cut out thin slices. Therefore, in order to improve the quality of medical paraffin in China and improve its competitiveness in the market, the development and research of medical paraffin wax is becoming more and more important.

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